An edition of Clostridium difficile (2010)

Clostridium difficile

methods and protocols

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Last edited by ImportBot
September 17, 2023 | History
An edition of Clostridium difficile (2010)

Clostridium difficile

methods and protocols

  • 1 Want to read

"Clostridium difficile is a major nosocomial pathogen and has been shown to be a primary cause of antibiotic-associated disease. Recently, there has been an emergence of highly transmissible and frequently antibiotic-resistant strains, and the organism has become a considerable burden on health-care systems worldwide. At the same time, there has been a dramatic increase in our ability to study the organism. This book brings together the key workers in C. difficile research to describe the recently developed methods for studying the organism. These range from methods for isolation of the organism, molecular typing, genomics, genetic manipulation, and the use of animal models. We are now therefore in a position to gain an in-depth understanding of how this organism is transmitted and how it causes disease."--P. v.

Publish Date
Publisher
Humana Press
Language
English
Pages
241

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Previews available in: English

Edition Availability
Cover of: Clostridium Difficile
Clostridium Difficile: Methods and Protocols
2018, Springer New York
in English
Cover of: Clostridium Difficile
Clostridium Difficile
2016, Springer New York
in English
Cover of: Clostridium Difficile
Clostridium Difficile: Methods and Protocols
2016, Humana Press
in English
Cover of: Clostridium difficile
Clostridium difficile: methods and protocols
2010, Humana Press
in English

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Book Details


Table of Contents

Part I. Introduction to Clostridium Difficile and the Disease It Causes
1. Clostridium difficile : No Longer an Enigmatic Pathogen? / Adam P. Roberts and Peter Mullany
2. Clostridium difficile and the Disease It Causes / Torbjörn Norén
Part II. Isolation and Culture Techniques
3. Clostridium difficile Isolation and Culture Techniques / Mike Wren
Part III. Methods for Typing and Epidemiological Studies
4. Molecular Typing Methods for Clostridium difficile : Pulsed-Field GelElectrophoresis and PCR Ribotyping / Sandra Janezic and Maja Rupnik
5. Clostridium difficile Toxinotyping / Maja Rupnik
6. Multilocus Sequence Typing for Clostridium difficile / Ludovic Lemée and Jean-Louis Pons
Part IV. Biochemistry of the Organism
7. Molecular Methods to Study Transcriptional Regulation of Clostridium difficile Toxin Genes / Ana Antunes and Bruno Dupuy
8. Dissecting the Cell Surface / Robert Fagan and Neil Fairweather
9. Human Intestinal Epithelial Response(s) to Clostridium difficile / Nazila V. Jafari, Elaine Allan, and Mona Bajaj-Elliott
Part V. Genomics
10. Comparative Genome Analysis of Clostridium difficile Using DNA Microarrays / Richard Stabler, Lisa Dawson, and Brendan Wren
Part VI. Development of Systems for Genetic Analysis of the Organism
11. ClosTron-Targeted Mutagenesis / John T. Heap, Stephen T. Cartman, Sarah A. Kuehne, Clare Cooksley, and Nigel P. Minton
12. Methods for Gene Cloning and Targeted Mutagenesis / Glen P. Carter, Dena Lyras, Rachael Poon, Pauline M. Howarth, and Julian I. Rood
13. Transposon Mutagenesis in Clostridium difficile / Haitham A. Hussain, Adam P. Roberts, Rachael Whalan, and Peter Mullany
Part VII. Animal Models of Disease
14. Refinement of the Hamster Model of Clostridium difficile Disease / Gillian Douce and David Goulding
15. Methods for Working with the Mouse Model / Anne Collignon.

Edition Notes

Includes bibliographical references and index.

Also issued online.

Published in
New York
Series
Springer protocols, Methods in molecular biology -- 646, Springer protocols, Methods in molecular biology (Clifton, N.J.) -- v. 646.

Classifications

Library of Congress
QR201.C54 C555 2010, QH301-705, QR

The Physical Object

Pagination
x, 241 p. :
Number of pages
241

ID Numbers

Open Library
OL25313758M
Internet Archive
clostridiumdiffi00mull
ISBN 10
1603273646, 1603273654
ISBN 13
9781603273640, 9781603273657
LCCN
2010923237
OCLC/WorldCat
506251780

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Download catalog record: RDF / JSON / OPDS | Wikipedia citation
September 17, 2023 Edited by ImportBot import existing book
January 2, 2023 Edited by MARC Bot import existing book
December 25, 2022 Edited by MARC Bot import existing book
December 25, 2021 Edited by ImportBot import existing book
May 16, 2012 Created by LC Bot Imported from Library of Congress MARC record